Ontology highlight
ABSTRACT:
SUBMITTER: Delgado-Escueta AV
PROVIDER: S-EPMC1874323 | biostudies-literature | 2007 May-Jun
REPOSITORIES: biostudies-literature
Epilepsy currents 20070501 3
One by one, mutation-containing mendelian genes that cause monogenic juvenile myoclonic epilepsies (JME) and single nucleotide polymorphisms (SNP)-susceptibility alleles that increase risks for nonmendelian complex JME should fall to the power of molecular genetics. Of 15 chromosome loci, 3 mendelian genes (alpha1-subunit of the GABA(A) receptor [GABRA1], chloride channel 2 gene [CLCN2], and Myoclonin1/EFHC1) and 2 SNP-susceptibility alleles of putative JME genes in epistases (bromodomain-contai ...[more]