Ontology highlight
ABSTRACT:
SUBMITTER: Joshi M
PROVIDER: S-EPMC1876681 | biostudies-literature | 2007 Apr
REPOSITORIES: biostudies-literature
Joshi Mandar M Jeoung Nam Ho NH Popov Kirill M KM Harris Robert A RA
Biochemical and biophysical research communications 20070228 1
A novel phosphatase has been cloned and partially characterized. It has a mitochondrial leader sequence and its amino acid sequence places it in the PP2C family like two known mitochondrial phosphatases. Western blot analysis of subcellular fractions and confocal microscopy of 3T3L1 preadipocytes expressing the GFP-tagged protein confirm its mitochondrial localization. Western blot analysis indicates that the protein is expressed in several mouse tissues, with highest expression in brain, heart, ...[more]