Role of Peyer's patches in the induction of Helicobacter pylori-induced gastritis.
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ABSTRACT:
SUBMITTER: Nagai S
PROVIDER: S-EPMC1885612 | biostudies-literature | 2007 May
REPOSITORIES: biostudies-literature
Publications
Role of Peyer's patches in the induction of Helicobacter pylori-induced gastritis.
Nagai Shigenori S Mimuro Hitomi H Yamada Taketo T Baba Yukiko Y Moro Kazuyo K Nochi Tomonori T Kiyono Hiroshi H Suzuki Toshihiko T Sasakawa Chihiro C Koyasu Shigeo S
Proceedings of the National Academy of Sciences of the United States of America 20070514 21
Helicobacter pylori is a Gram-negative spiral bacterium that causes gastritis and peptic ulcer and has been implicated in the pathogenesis of gastric adenocarcinoma and mucosa-associated lymphoid tissue lymphoma. Although Th1 immunity is involved in gastritis and the accumulation of H. pylori-specific CD4(+) T cells in the H. pylori-infected gastric mucosa in human patients, how T cells are primed with H. pylori antigens is unknown because no apparent lymphoid tissues are present in the stomach. ...[more]
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2023-12-04 | PXD046333 | Pride
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