Mapping biomedical concepts onto the human genome by mining literature on chromosomal aberrations.
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ABSTRACT:
SUBMITTER: Van Vooren S
PROVIDER: S-EPMC1885641 | biostudies-literature | 2007
REPOSITORIES: biostudies-literature
Publications
Mapping biomedical concepts onto the human genome by mining literature on chromosomal aberrations.
Van Vooren Steven S Thienpont Bernard B Menten Björn B Speleman Frank F De Moor Bart B Vermeesch Joris J Moreau Yves Y
Nucleic acids research 20070401 8
Biomedical literature provides a rich but unstructured source of associations between chromosomal regions and biomedical concepts. By mining MEDLINE abstracts, we annotate the human genome at the level of cytogenetic bands. Our method creates a set of chromosomal aberration maps that associate cytogenetic bands to biomedical concepts from a variety of controlled vocabularies, including disease, dysmorphology, anatomy, development and Gene Ontology branches. The association between a band (e.g. 4 ...[more]
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