Ontology highlight
ABSTRACT:
SUBMITTER: Bacani J
PROVIDER: S-EPMC1888489 | biostudies-literature | 2005 Oct
REPOSITORIES: biostudies-literature
Bacani Julinor J Zwingerman Rhonda R Di Nicola Nando N Spencer Samantha S Wegrynowski Trish T Mitchell Kyle K Hay Kazuko K Redston Mark M Holowaty Eric E Huntsman David D Pollett Aaron A Riddell Robert R Gallinger Steven S
The Journal of molecular diagnostics : JMD 20051001 4
Gastric cancer (GC) remains a leading cause of cancer mortality worldwide. Genetic factors are implicated, including DNA mismatch repair (MMR) deficiency manifested as tumor microsatellite instability (MSI). However, a standardized panel of markers and a definition of low-versus-high level MSI in GC are lacking. We examined a population-based cohort of early onset (<or=50 yrs) gastric cancer. We identified 211 cases of early onset gastric cancer in Central-East Ontario from 1989 to 1993, with ar ...[more]