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Staphylococcus aureus strains that are hypersusceptible to resistance gene transfer from enterococci.


ABSTRACT: We identified naturally occurring Staphylococcus aureus mutants of the restriction modification pathway SauI, including bovine lineage ST151. In a model of vancomycin resistance transfer from Enterococcus faecalis, ST151 isolates are 500 times more susceptible than human S. aureus isolates. The eradication of "hyperrecipient" strains may reduce the evolution of vancomycin-resistant S. aureus.

SUBMITTER: Sung JM 

PROVIDER: S-EPMC1891402 | biostudies-literature | 2007 Jun

REPOSITORIES: biostudies-literature

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Staphylococcus aureus strains that are hypersusceptible to resistance gene transfer from enterococci.

Sung Julia M-L JM   Lindsay Jodi A JA  

Antimicrobial agents and chemotherapy 20070319 6


We identified naturally occurring Staphylococcus aureus mutants of the restriction modification pathway SauI, including bovine lineage ST151. In a model of vancomycin resistance transfer from Enterococcus faecalis, ST151 isolates are 500 times more susceptible than human S. aureus isolates. The eradication of "hyperrecipient" strains may reduce the evolution of vancomycin-resistant S. aureus. ...[more]

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