Ontology highlight
ABSTRACT:
SUBMITTER: Chen W
PROVIDER: S-EPMC1895737 | biostudies-literature | 2006 Mar
REPOSITORIES: biostudies-literature
Chen Weiyi W Houldsworth Jane J Olshen Adam B AB Nanjangud Gouri G Chaganti Seeta S Venkatraman Ennapadem S ES Halaas Jeffrey J Teruya-Feldstein Julie J Zelenetz Andrew D AD Chaganti R S K RS
Blood 20051129 6
To identify, in high-resolution regions of DNA, the copy number changes associated with outcome in patients with diffuse large B-cell lymphoma (DLBCL), a disease with an approximately 50% mortality rate, we performed array comparative genomic hybridization (array-CGH) on specimens from 64 patients with newly diagnosed DLBCL treated with anthracycline-based chemotherapy. For the entire cohort, 55 commonly gained/lost regions, ranging in size from less than 1 Mbp to entire chromosomes, were identi ...[more]