Ontology highlight
ABSTRACT:
SUBMITTER: Zhang D
PROVIDER: S-EPMC1896291 | biostudies-literature | 2007 Jun
REPOSITORIES: biostudies-literature
Zhang Dan D Boulware Michael J MJ Pendleton Matthew R MR Nogi Taisaku T Marchant Jonathan S JS
The Biochemical journal 20070601 3
Studies in the Xenopus model system have provided considerable insight into the developmental role of intracellular Ca2+ signals produced by activation of IP3Rs (inositol 1,4,5-trisphosphate receptors). However, unlike mammalian systems where three IP3R subtypes have been well characterized, our molecular understanding of the IP3Rs that underpin Ca2+ signalling during Xenopus embryogenesis relate solely to the original characterization of the 'Xenopus IP3R' cloned and purified from Xenopus laevi ...[more]