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A systematic comparative and structural analysis of protein phosphorylation sites based on the mtcPTM database.

ABSTRACT: mtcPTM is an online repository of human and mouse phosphosites in which data are hierarchically organized to preserve biologically relevant experimental information, thus allowing straightforward comparisons of phosphorylation patterns found under different conditions. The database also contains the largest available collection of atomic models of phosphorylatable proteins. Detailed analysis of this structural dataset reveals that phosphorylation sites are found in a heterogeneous range of structural and sequence contexts. mtcPTM is available on the web http://www.mitocheck.org/cgi-bin/mtcPTM/search.

SUBMITTER: Jimenez JL

PROVIDER: S-EPMC1929158 | biostudies-literature | 2007

REPOSITORIES: biostudies-literature

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A systematic comparative and structural analysis of protein phosphorylation sites based on the mtcPTM database.

Jiménez José L JL Hegemann Björn B Hutchins James R A JR Peters Jan-Michael JM Durbin Richard R

Genome biology 20070101 5

mtcPTM is an online repository of human and mouse phosphosites in which data are hierarchically organized to preserve biologically relevant experimental information, thus allowing straightforward comparisons of phosphorylation patterns found under different conditions. The database also contains the largest available collection of atomic models of phosphorylatable proteins. Detailed analysis of this structural dataset reveals that phosphorylation sites are found in a heterogeneous range of struc ...[more]

PMID: 17521420

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