RTX toxin actin cross-linking activity in clinical and environmental isolates of Vibrio cholerae.
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ABSTRACT:
SUBMITTER: Cordero CL
PROVIDER: S-EPMC1932970 | biostudies-literature | 2007 Jul
REPOSITORIES: biostudies-literature
Publications
RTX toxin actin cross-linking activity in clinical and environmental isolates of Vibrio cholerae.
Cordero Christina L CL Sozhamannan Shanmuga S Satchell Karla J Fullner KJ
Journal of clinical microbiology 20070523 7
Vibrio cholerae strains from diverse O-antigen groups were evaluated for RTX toxin actin cross-linking activity. This study demonstrates that the actin cross-linking domain sequence is present within rtxA in the majority of clinical and environmental isolates tested, and the RTX toxin produced by these strains catalyzes the covalent cross-linking of cellular actin. ...[more]
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