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Development of a serological assay based on a synthetic peptide selected from the VP0 capsid protein for detection of human parechoviruses.

ABSTRACT: A serological enzyme-linked immunosorbent assay was developed using a synthetic peptide from the VP0 protein of human parechoviruses (HPeVs). Seroprevalence for HPeVs was 70% in children of < or = 5 years of age and 95% in adults. For children from whom serial sera were sampled, seropositivity increased from 22% to 88% between 2 and 24 months of age.

SUBMITTER: Abed Y

PROVIDER: S-EPMC1933058 | biostudies-literature | 2007 Jun

REPOSITORIES: biostudies-literature

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Development of a serological assay based on a synthetic peptide selected from the VP0 capsid protein for detection of human parechoviruses.

Abed Yacine Y Wolf Dana D Dagan Ron R Boivin Guy G

Journal of clinical microbiology 20070418 6

A serological enzyme-linked immunosorbent assay was developed using a synthetic peptide from the VP0 protein of human parechoviruses (HPeVs). Seroprevalence for HPeVs was 70% in children of < or = 5 years of age and 95% in adults. For children from whom serial sera were sampled, seropositivity increased from 22% to 88% between 2 and 24 months of age. ...[more]

PMID: 17442804

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