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ISACGH: a web-based environment for the analysis of Array CGH and gene expression which includes functional profiling.


ABSTRACT: We present the ISACGH, a web-based system that allows for the combination of genomic data with gene expression values and provides different options for functional profiling of the regions found. Several visualization options offer a convenient representation of the results. Different efficient methods for accurate estimation of genomic copy number from array-CGH hybridization data have been included in the program. Moreover, the connection to the gene expression analysis package GEPAS allows the use of different facilities for data pre-processing and analysis. A DAS server allows exporting the results to the Ensembl viewer where contextual genomic information can be obtained. The program is freely available at: http://isacgh.bioinfo.cipf.es or within http://www.gepas.org.

SUBMITTER: Conde L 

PROVIDER: S-EPMC1933149 | biostudies-literature | 2007 Jul

REPOSITORIES: biostudies-literature

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ISACGH: a web-based environment for the analysis of Array CGH and gene expression which includes functional profiling.

Conde Lucía L   Montaner David D   Burguet-Castell Jordi J   Tárraga Joaquín J   Medina Ignacio I   Al-Shahrour Fátima F   Dopazo Joaquín J  

Nucleic acids research 20070427 Web Server issue


We present the ISACGH, a web-based system that allows for the combination of genomic data with gene expression values and provides different options for functional profiling of the regions found. Several visualization options offer a convenient representation of the results. Different efficient methods for accurate estimation of genomic copy number from array-CGH hybridization data have been included in the program. Moreover, the connection to the gene expression analysis package GEPAS allows th  ...[more]

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