Ontology highlight
ABSTRACT:
SUBMITTER: Tsunoda M
PROVIDER: S-EPMC1934993 | biostudies-literature | 2007
REPOSITORIES: biostudies-literature
Tsunoda Masaru M Kusakabe Yoshio Y Tanaka Nobutada N Ohno Satoshi S Nakamura Masashi M Senda Toshiya T Moriguchi Tomohisa T Asai Norio N Sekine Mitsuo M Yokogawa Takashi T Nishikawa Kazuya K Nakamura Kazuo T KT
Nucleic acids research 20070618 13
The specific aminoacylation of tRNA by tyrosyl-tRNA synthetases (TyrRSs) relies on the identity determinants in the cognate tRNA(Tyr)s. We have determined the crystal structure of Saccharomyces cerevisiae TyrRS (SceTyrRS) complexed with a Tyr-AMP analog and the native tRNA(Tyr)(GPsiA). Structural information for TyrRS-tRNA(Tyr) complexes is now full-line for three kingdoms. Because the archaeal/eukaryotic TyrRSs-tRNA(Tyr)s pairs do not cross-react with their bacterial counterparts, the recogniti ...[more]