Strictly polyphosphate-dependent glucokinase in a polyphosphate-accumulating bacterium, Microlunatus phosphovorus.
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ABSTRACT:
SUBMITTER: Tanaka S
PROVIDER: S-EPMC193765 | biostudies-literature | 2003 Sep
REPOSITORIES: biostudies-literature
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Strictly polyphosphate-dependent glucokinase in a polyphosphate-accumulating bacterium, Microlunatus phosphovorus.
Tanaka Shotaro S Lee Sun-Og SO Hamaoka Kazuhiro K Kato Junichi J Takiguchi Noboru N Nakamura Kazunori K Ohtake Hisao H Kuroda Akio A
Journal of bacteriology 20030901 18
ATP-dependent glucokinase is suggested to have evolved from a hypothetical polyphosphate (polyP)-dependent glucokinase (polyP-GK) via a bifunctional polyP/ATP glucokinase (polyP/ATP-GK). Here we showed that polyP-GK is present in a polyP-accumulating bacterium, Microlunatus phosphovorus. The polyP-GK produced glucose-6-P(i) from glucose and polyP, but it could not phosphorylate glucose with ATP. The polyP-GK was most closely related to the polyP/ATP-GK of Mycobacterium tuberculosis. ...[more]
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