Bioinformatics approaches to classifying allergens and predicting cross-reactivity.
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ABSTRACT:
SUBMITTER: Schein CH
PROVIDER: S-EPMC1941676 | biostudies-literature | 2007 Feb
REPOSITORIES: biostudies-literature
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Bioinformatics approaches to classifying allergens and predicting cross-reactivity.
Schein Catherine H CH Ivanciuc Ovidiu O Braun Werner W
Immunology and allergy clinics of North America 20070201 1
Allergenic proteins from very different environmental sources have similar sequences and structures. This fact may account for multiple allergen syndromes, whereby a myriad of diverse plants and foods may induce a similar IgE-based reaction in certain patients. Identifying the common triggering protein in these sources, in silico, can aid designing individualized therapy for allergen sufferers. This article provides an overview of databases on allergenic proteins, and ways to identify common pro ...[more]
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