The COMT Val158Met polymorphism and temporal lobe morphometry in healthy adults.
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ABSTRACT:
SUBMITTER: Taylor WD
PROVIDER: S-EPMC1950247 | biostudies-literature | 2007 Jul
REPOSITORIES: biostudies-literature
Publications
The COMT Val158Met polymorphism and temporal lobe morphometry in healthy adults.
Taylor Warren D WD Züchner Stephan S Payne Martha E ME Messer Denise F DF Doty Tracy J TJ MacFall James R JR Beyer John L JL Krishnan K Ranga R KR
Psychiatry research 20070523 2
We examined the relationship between COMT Val158Met genotype and temporal lobe volumes, including the caudate as a control region. Thirty-one healthy subjects completed 1.5T brain MRI and genotyping. After controlling for demographics, Val158 allele homozygotes exhibited significantly smaller temporal lobe and hippocampal volumes, with a trend for smaller amygdala volumes. ...[more]
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