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Left ventricular form and function revisited: applied translational science to cardiovascular ultrasound imaging.


ABSTRACT: Doppler tissue imaging (DTI) and DTI-derived strain imaging are robust physiologic tools used for the noninvasive assessment of regional myocardial function. As a result of high temporal and spatial resolution, regional function can be assessed for each phase of the cardiac cycle and within the transmural layers of the myocardial wall. Newer techniques that measure myocardial motion by speckle tracking in gray-scale images have overcome the angle dependence of DTI strain, allowing for measurement of 2-dimensional strain and cardiac rotation. DTI, DTI strain, and speckle tracking may provide unique information that deciphers the deformation sequence of complexly oriented myofibers in the left ventricular wall. The data are, however, limited. This review examines the structure and function of the left ventricle relative to the potential clinical application of DTI and speckle tracking in assessing the global mechanical sequence of the left ventricle in vivo.

SUBMITTER: Sengupta PP 

PROVIDER: S-EPMC1951787 | biostudies-literature | 2007 May

REPOSITORIES: biostudies-literature

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Left ventricular form and function revisited: applied translational science to cardiovascular ultrasound imaging.

Sengupta Partho P PP   Krishnamoorthy Vijay K VK   Korinek Josef J   Narula Jagat J   Vannan Mani A MA   Lester Steven J SJ   Tajik Jamil A JA   Seward James B JB   Khandheria Bijoy K BK   Belohlavek Marek M  

Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography 20070501 5


Doppler tissue imaging (DTI) and DTI-derived strain imaging are robust physiologic tools used for the noninvasive assessment of regional myocardial function. As a result of high temporal and spatial resolution, regional function can be assessed for each phase of the cardiac cycle and within the transmural layers of the myocardial wall. Newer techniques that measure myocardial motion by speckle tracking in gray-scale images have overcome the angle dependence of DTI strain, allowing for measuremen  ...[more]

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