Genetic structure of the nadA and nadB antivirulence loci in Shigella spp.
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ABSTRACT:
SUBMITTER: Prunier AL
PROVIDER: S-EPMC1951923 | biostudies-literature | 2007 Sep
REPOSITORIES: biostudies-literature
Publications
Genetic structure of the nadA and nadB antivirulence loci in Shigella spp.
Prunier Anne-Laure AL Schuch Raymond R Fernández Reinaldo E RE Maurelli Anthony T AT
Journal of bacteriology 20070622 17
Comparison of nadA and nadB in 14 Shigella strains and enteroinvasive Escherichia coli versus E. coli showed that at least one locus is altered in all strains. These observations explain the characteristic nicotinic acid auxotrophy of Shigella organisms and are consistent with the previously identified antivirulence nature of these genes for these pathogens. ...[more]
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