Pseudomonas aeruginosa forms biofilms in acute infection independent of cell-to-cell signaling.
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ABSTRACT:
SUBMITTER: Schaber JA
PROVIDER: S-EPMC1952004 | biostudies-literature | 2007 Aug
REPOSITORIES: biostudies-literature
Publications
Pseudomonas aeruginosa forms biofilms in acute infection independent of cell-to-cell signaling.
Schaber J Andy JA Triffo W Jeffrey WJ Suh Sang Jin SJ Oliver Jeffrey W JW Hastert Mary Catherine MC Griswold John A JA Auer Manfred M Hamood Abdul N AN Rumbaugh Kendra P KP
Infection and immunity 20070611 8
Biofilms are bacterial communities residing within a polysaccharide matrix that are associated with persistence and antibiotic resistance in chronic infections. We show that the opportunistic pathogen Pseudomonas aeruginosa forms biofilms within 8 h of infection in thermally injured mice, demonstrating that biofilms contribute to bacterial colonization in acute infections as well. Using light, electron, and confocal scanning laser microscopy, P. aeruginosa biofilms were visualized within burned ...[more]
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