Ontology highlight
ABSTRACT:
SUBMITTER: Grenha R
PROVIDER: S-EPMC1952315 | biostudies-literature | 2005 May
REPOSITORIES: biostudies-literature
Grenha Rosa R Levdikov Vladimir M VM Fogg Mark J MJ Blagova Elena V EV Brannigan James A JA Wilkinson Anthony J AJ Wilson Keith S KS
Acta crystallographica. Section F, Structural biology and crystallization communications 20050409 Pt 5
Protein structures from the causative agent of anthrax (Bacillus anthracis) are being determined as part of a structural genomics programme. Amongst initial candidates for crystallographic analysis are enzymes involved in nucleotide biosynthesis, since these are recognized as potential targets in antibacterial therapy. Purine nucleoside phosphorylase is a key enzyme in the purine-salvage pathway. The crystal structure of purine nucleoside phosphorylase (DeoD) from B. anthracis has been solved by ...[more]