Ontology highlight
ABSTRACT:
SUBMITTER: Dontsova MV
PROVIDER: S-EPMC1952443 | biostudies-literature | 2005 Apr
REPOSITORIES: biostudies-literature
Dontsova Maria V MV Gabdoulkhakov Azat G AG Molchan Olga K OK Lashkov Alexandr A AA Garber Maria B MB Mironov Alexandr S AS Zhukhlistova Nadegda E NE Morgunova Ekaterina Yu EY Voelter Wolfgang W Betzel Christian C Zhang Yang Y Ealick Steven E SE Mikhailov Al'bert M AM
Acta crystallographica. Section F, Structural biology and crystallization communications 20050324 Pt 4
Uridine phosphorylase (UPh) catalyzes the phosphorolytic cleavage of the C-N glycosidic bond of uridine to ribose 1-phosphate and uracil in the pyrimidine-salvage pathway. The crystal structure of the Salmonella typhimurium uridine phosphorylase (StUPh) has been determined at 2.5 A resolution and refined to an R factor of 22.1% and an Rfree of 27.9%. The hexameric StUPh displays 32 point-group symmetry and utilizes both twofold and threefold non-crystallographic axes. A phosphate is bound at the ...[more]