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ABSTRACT:
SUBMITTER: Koretke KK
PROVIDER: S-EPMC19672 | biostudies-literature | 1998 Mar
REPOSITORIES: biostudies-literature
Koretke K K KK Luthey-Schulten Z Z Wolynes P G PG
Proceedings of the National Academy of Sciences of the United States of America 19980301 6
The protein energy landscape theory is used to obtain optimal energy functions for protein structure prediction via simulated annealing. The analysis here takes advantage of a more complete statistical characterization of the protein energy landscape and thereby improves on previous approximations. This schema partially takes into account correlations in the energy landscape. It also incorporates the relationships between folding dynamics and characteristic energy scales that control the collaps ...[more]