Ontology highlight
ABSTRACT:
SUBMITTER: Hollingsworth JW
PROVIDER: S-EPMC1976546 | biostudies-literature | 2007 Aug
REPOSITORIES: biostudies-literature
Hollingsworth John W JW Li Zhuowei Z Brass David M DM Garantziotis Stavros S Timberlake Sarah H SH Kim Andrew A Hossain Imtaz I Savani Rashmin C RC Schwartz David A DA
American journal of respiratory cell and molecular biology 20070419 2
LPS from bacteria is ubiquitous in the environment and can cause airway disease and modify allergic asthma. Identification of gene products that modulate the biologic response to inhaled LPS will improve our understanding of inflammatory airways disease. Previous work has identified quantitative trait loci for the response to inhaled LPS on chromosomes 2 and 11. In these regions, 28 genes had altered RNA expression after inhalation of LPS, including CD44, which was associated with differences in ...[more]