Ontology highlight
ABSTRACT:
SUBMITTER: Yun TJ
PROVIDER: S-EPMC19800 | biostudies-literature | 1997 Feb
REPOSITORIES: biostudies-literature
Yun T J TJ Melvold R W RW Pease L R LR
Proceedings of the National Academy of Sciences of the United States of America 19970201 4
A spontaneous variant of the mouse class I major histocompatibility complex D(b) gene, designated D(bm28), is characterized. This mutation consists of a cluster of nucleotide substitutions in exon 3 that resembles the product of a classical gene conversion event in that the substituted nucleotides appear to be templated. However, D(bm28) is distinctive, because no single donor gene containing the nucleotide sequence of the mutation exists in the genome of the parent strain. The mutation is consi ...[more]