Ontology highlight
ABSTRACT:
SUBMITTER: Ray A
PROVIDER: S-EPMC1986798 | biostudies-literature | 2007 Feb
REPOSITORIES: biostudies-literature
Neuron 20070201 3
A remarkable problem in neurobiology is how olfactory receptor neurons (ORNs) select, from among a large odor receptor repertoire, which receptors to express. We use computational algorithms and mutational analysis to define positive and negative regulatory elements that are required for selection of odor receptor (Or) genes in the proper olfactory organ of Drosophila, and we identify an element that is essential for selection in one ORN class. Two odor receptors are coexpressed by virtue of the ...[more]