Ontology highlight
ABSTRACT:
SUBMITTER: Manzini MC
PROVIDER: S-EPMC2020849 | biostudies-literature | 2007 Jun
REPOSITORIES: biostudies-literature
Manzini M Chiara MC Joseph Donald J DJ MacDermott Amy B AB Mason Carol A CA
Molecular and cellular neurosciences 20070324 2
While neuronal cultures are an established model for analyzing excitotoxic brain injury in the adult, in vitro systems have not been extensively employed to study how developing neurons respond to levels of excitatory compounds that are lethal to mature neurons. Recently, we reported that the in vivo differentiation programs of cerebellar granule cells (CGNs) are recapitulated in purified CGN cultures [Manzini M.C., Ward M.S., Zhang Q., Lieberman M.D., Mason C.A. (2006) The stop-signal revised: ...[more]