Ontology highlight
ABSTRACT:
SUBMITTER: Nishida KM
PROVIDER: S-EPMC2040086 | biostudies-literature | 2007 Nov
REPOSITORIES: biostudies-literature
Nishida Kazumichi M KM Saito Kuniaki K Mori Tomoko T Kawamura Yoshinori Y Nagami-Okada Tomoko T Inagaki Sachi S Siomi Haruhiko H Siomi Mikiko C MC
RNA (New York, N.Y.) 20070913 11
Genetic studies have shown that Aubergine (Aub), one of the Piwi subfamily of Argonautes in Drosophila, is essential for germ cell formation and maintaining fertility. aub mutations lead to the accumulation of retrotransposons in ovaries and testes, and Stellate transcripts in testes. Aub in ovaries associates with a variety of Piwi-interacting RNAs (piRNAs) derived from repetitive intergenic elements including retrotransposons. Here we found that Aub in testes also associates with various kinds ...[more]