Ontology highlight
ABSTRACT:
SUBMITTER: Balinsky CA
PROVIDER: S-EPMC2045533 | biostudies-literature | 2007 Oct
REPOSITORIES: biostudies-literature
Balinsky C A CA Delhon G G Afonso C L CL Risatti G R GR Borca M V MV French R A RA Tulman E R ER Geary S J SJ Rock D L DL
Journal of virology 20070808 20
Sheeppox virus (SPPV), a member of the Capripoxvirus genus of the Poxviridae, is the etiologic agent of a significant disease of sheep in the developing world. Genomic analysis of pathogenic and vaccine capripoxviruses identified genes with potential roles in virulence and host range, including three genes with similarity to kelch-like genes of other poxviruses and eukaryotes. Here, a mutant SPPV with a deletion in the SPPV-019 kelch-like gene, DeltaKLP, was derived from the pathogenic strain SP ...[more]