Membrane binding domains.
Ontology highlight
ABSTRACT:
SUBMITTER: Hurley JH
PROVIDER: S-EPMC2049088 | biostudies-literature | 2006 Aug
REPOSITORIES: biostudies-literature
Publications
Eukaryotic signaling and trafficking proteins are rich in modular domains that bind cell membranes. These binding events are tightly regulated in space and time. The structural, biochemical, and biophysical mechanisms for targeting have been worked out for many families of membrane binding domains. This review takes a comparative view of seven major classes of membrane binding domains, the C1, C2, PH, FYVE, PX, ENTH, and BAR domains. These domains use a combination of specific headgroup interact ...[more]
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