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ABSTRACT:
SUBMITTER: Grosshans BL
PROVIDER: S-EPMC2063532 | biostudies-literature | 2006 Jan
REPOSITORIES: biostudies-literature
Grosshans Bianka L BL Andreeva Anna A Gangar Akanksha A Niessen Sherry S Yates John R JR Brennwald Patrick P Novick Peter P
The Journal of cell biology 20060101 1
Rab guanosine triphosphatases regulate intracellular membrane traffic by binding specific effector proteins. The yeast Rab Sec4p plays multiple roles in the polarized transport of post-Golgi vesicles to, and their subsequent fusion with, the plasma membrane, suggesting the involvement of several effectors. Yet, only one Sec4p effector has been documented to date: the exocyst protein Sec15p. The exocyst is an octameric protein complex required for tethering secretory vesicles, which is a prerequi ...[more]