Drosophila melanogaster Scramblases modulate synaptic transmission.
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ABSTRACT:
SUBMITTER: Acharya U
PROVIDER: S-EPMC2063791 | biostudies-literature | 2006 Apr
REPOSITORIES: biostudies-literature
Publications
Drosophila melanogaster Scramblases modulate synaptic transmission.
Acharya Usha U Edwards Michael Beth MB Jorquera Ramon A RA Silva Hugo H Nagashima Kunio K Labarca Pedro P Acharya Jairaj K JK
The Journal of cell biology 20060401 1
Scramblases are a family of single-pass plasma membrane proteins, identified by their purported ability to scramble phospholipids across the two layers of plasma membrane isolated from platelets and red blood cells. However, their true in vivo role has yet to be elucidated. We report the generation and isolation of null mutants of two Scramblases identified in Drosophila melanogaster. We demonstrate that flies lacking either or both of these Scramblases are not compromised in vivo in processes r ...[more]
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