Ontology highlight
ABSTRACT:
SUBMITTER: Kuhlenbaumer G
PROVIDER: S-EPMC2077513 | biostudies-literature | 2006 Apr
REPOSITORIES: biostudies-literature
Kuhlenbäumer G G Berger K K Huge A A Lange E E Kessler C C John U U Funke H H Nabavi D G DG Stögbauer F F Ringelstein E B EB Stoll M M
Journal of neurology, neurosurgery, and psychiatry 20060401 4
Genetic fine mapping of the first locus identified for genetically complex forms of stroke, STRK1 (which has been mapped to chromosome 5q12 in Icelandic families), has identified the phosphodiesterase 4D gene (PDE4D) gene as a good candidate gene. Association analysis of single nucleotide polymorphisms (SNPs) in the PDE4D gene in an Icelandic stroke cohort demonstrated genetic association between six SNPs in the 5' region of PDE4D and ischaemic stroke. The present study aimed to test whether the ...[more]