Neuronal spatiotemporal pattern discrimination: the dynamical evolution of seizures.
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ABSTRACT:
SUBMITTER: Schiff SJ
PROVIDER: S-EPMC2078330 | biostudies-literature | 2005 Dec
REPOSITORIES: biostudies-literature
Publications
Neuronal spatiotemporal pattern discrimination: the dynamical evolution of seizures.
Schiff Steven J SJ Sauer Tim T Kumar Rohit R Weinstein Steven L SL
NeuroImage 20050928 4
We developed a modern numerical approach to the multivariate linear discrimination of Fisher from 1936 based upon singular value decomposition that is sufficiently stable to permit widespread application to spatiotemporal neuronal patterns. We demonstrate this approach on an old problem in neuroscience--whether seizures have distinct dynamical states as they evolve with time. A practical result was the first demonstration that human seizures have distinct initiation and termination dynamics, an ...[more]
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