Ontology highlight
ABSTRACT:
SUBMITTER: Placido D
PROVIDER: S-EPMC2082211 | biostudies-literature | 2007 Apr
REPOSITORIES: biostudies-literature
Placido Diana D Brown Bernard A BA Lowenhaupt Ky K Rich Alexander A Athanasiadis Alekos A
Structure (London, England : 1993) 20070401 4
The A form RNA double helix can be transformed to a left-handed helix, called Z-RNA. Currently, little is known about the detailed structural features of Z-RNA or its involvement in cellular processes. The discovery that certain interferon-response proteins have domains that can stabilize Z-RNA as well as Z-DNA opens the way for the study of Z-RNA. Here, we present the 2.25 A crystal structure of the Zalpha domain of the RNA-editing enzyme ADAR1 (double-stranded RNA adenosine deaminase) complexe ...[more]