Ontology highlight
ABSTRACT:
SUBMITTER: Lamb RA
PROVIDER: S-EPMC2086805 | biostudies-literature | 2007 Aug
REPOSITORIES: biostudies-literature
Lamb Robert A RA Jardetzky Theodore S TS
Current opinion in structural biology 20070801 4
The structures of glycoproteins that mediate enveloped virus entry into cells have revealed dramatic structural changes that accompany membrane fusion and provided mechanistic insights into this process. The group of class I viral fusion proteins includes the influenza hemagglutinin, paramyxovirus F, HIV env, and other mechanistically related fusogens, but these proteins are unrelated in sequence and exhibit clearly distinct structural features. Recently determined crystal structures of the para ...[more]