Ontology highlight
ABSTRACT:
SUBMITTER: Nakamura M
PROVIDER: S-EPMC2132962 | biostudies-literature | 1998 Nov
REPOSITORIES: biostudies-literature
Nakamura M M Masuda H H Horii J J Kuma K i Ki Yokoyama N N Ohba T T Nishitani H H Miyata T T Tanaka M M Nishimoto T T
The Journal of cell biology 19981101 4
A novel human protein with a molecular mass of 55 kD, designated RanBPM, was isolated with the two-hybrid method using Ran as a bait. Mouse and hamster RanBPM possessed a polypeptide identical to the human one. Furthermore, Saccharomyces cerevisiae was found to have a gene, YGL227w, the COOH-terminal half of which is 30% identical to RanBPM. Anti-RanBPM antibodies revealed that RanBPM was localized within the centrosome throughout the cell cycle. Overexpression of RanBPM produced multiple spots ...[more]