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Stretching to understand proteins - a survey of the protein data bank.


ABSTRACT: We make a survey of resistance of 7510 proteins to mechanical stretching at constant speed as studied within a coarse-grained molecular dynamics model. We correlate the maximum force of resistance with the native structure, predict proteins which should be especially strong, and identify the nature of their force clamps.

SUBMITTER: Sulkowska JI 

PROVIDER: S-EPMC2134851 | biostudies-literature | 2008 Jan

REPOSITORIES: biostudies-literature

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Stretching to understand proteins - a survey of the protein data bank.

Sułkowska Joanna I JI   Cieplak Marek M  

Biophysical journal 20070817 1


We make a survey of resistance of 7510 proteins to mechanical stretching at constant speed as studied within a coarse-grained molecular dynamics model. We correlate the maximum force of resistance with the native structure, predict proteins which should be especially strong, and identify the nature of their force clamps. ...[more]

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