Dynamical quorum sensing: Population density encoded in cellular dynamics.
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ABSTRACT:
SUBMITTER: De Monte S
PROVIDER: S-EPMC2141785 | biostudies-literature | 2007 Nov
REPOSITORIES: biostudies-literature
Publications
Dynamical quorum sensing: Population density encoded in cellular dynamics.
De Monte Silvia S d'Ovidio Francesco F Danø Sune S Sørensen Preben Graae PG
Proceedings of the National Academy of Sciences of the United States of America 20071114 47
Mutual synchronization by exchange of chemicals is a mechanism for the emergence of collective dynamics in cellular populations. General theories exist on the transition to coherence, but no quantitative, experimental demonstration has been given. Here, we present a modeling and experimental analysis of cell-density-dependent glycolytic oscillations in yeast. We study the disappearance of oscillations at low cell density and show that this phenomenon occurs synchronously in all cells and not by ...[more]
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