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Transposase-derived transcription factors regulate light signaling in Arabidopsis.

ABSTRACT: Plants use light to optimize growth and development. The photoreceptor phytochrome A (phyA) mediates various far-red light-induced responses. We show that Arabidopsis FHY3 and FAR1, which encode two proteins related to Mutator-like transposases, act together to modulate phyA signaling by directly activating the transcription of FHY1 and FHL, whose products are essential for light-induced phyA nuclear accumulation and subsequent light responses. FHY3 and FAR1 have separable DNA binding and transcriptional activation domains that are highly conserved in Mutator-like transposases. Further, expression of FHY3 and FAR1 is negatively regulated by phyA signaling. We propose that FHY3 and FAR1 represent transcription factors that have been co-opted from an ancient Mutator-like transposase(s) to modulate phyA-signaling homeostasis in higher plants.

SUBMITTER: Lin R

PROVIDER: S-EPMC2151751 | biostudies-literature | 2007 Nov

REPOSITORIES: biostudies-literature

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Transposase-derived transcription factors regulate light signaling in Arabidopsis.

Lin Rongcheng R Ding Lei L Casola Claudio C Ripoll Daniel R DR Feschotte Cédric C Wang Haiyang H

Science (New York, N.Y.) 20071101 5854

Plants use light to optimize growth and development. The photoreceptor phytochrome A (phyA) mediates various far-red light-induced responses. We show that Arabidopsis FHY3 and FAR1, which encode two proteins related to Mutator-like transposases, act together to modulate phyA signaling by directly activating the transcription of FHY1 and FHL, whose products are essential for light-induced phyA nuclear accumulation and subsequent light responses. FHY3 and FAR1 have separable DNA binding and transc ...[more]

PMID: 18033885

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