Ontology highlight
ABSTRACT:
SUBMITTER: Krause DR
PROVIDER: S-EPMC2168328 | biostudies-literature | 2007 Dec
REPOSITORIES: biostudies-literature
Krause Darren R DR Gatton Michelle L ML Frankland Sarah S Eisen Damon P DP Good Michael F MF Tilley Leann L Cheng Qin Q
Infection and immunity 20071008 12
The immune response against the Plasmodium falciparum variant surface antigen P. falciparum erythrocyte membrane protein 1 (PfEMP1) is a key component of clinical immunity against falciparum malaria. In this study, we used sera from human volunteers who had been infected with the P. falciparum 3D7 strain to investigate the development, specificity, and dynamics of anti-PfEMP1 antibodies measured against six different strain 3D7 Duffy binding-like domain 1alpha (DBL1alpha) fusion proteins. We obs ...[more]