Ontology highlight
ABSTRACT:
SUBMITTER: Tisserant A
PROVIDER: S-EPMC2169300 | biostudies-literature | 2008 Jan
REPOSITORIES: biostudies-literature
PloS one 20080109 1
Alternative splicing of transcripts in a signal-dependent manner has emerged as an important concept to ensure appropriate expression of splice variants under different conditions. Binding of the general splicing factor U2AF to splice sites preceding alternatively spliced exons has been suggested to be an important step for splice site recognition. For splicing to proceed, U2AF has to be replaced by other factors. We show here that U2AF interacts with the signal-dependent splice regulator Sam68 ...[more]