Ontology highlight
ABSTRACT:
SUBMITTER: Das S
PROVIDER: S-EPMC2170890 | biostudies-literature | 2007 Nov
REPOSITORIES: biostudies-literature
Das Sudipto S Ise Tomoko T Nagata Satoshi S Maeda Hiroshi H Bera Tapan K TK Pastan Ira I
Biochemical and biophysical research communications 20070921 3
The POTE gene family is composed of 13 paralogs and likely evolved by duplications and remodeling of the human genome. One common property of POTE proteins is their localization on the inner aspect of the plasma membrane. To determine the structural elements required for membrane localization, we expressed mutants of different POTEs in 293T cells as EGFP fusion proteins. We also tested their palmitoylation by a biotin-switch assay. Our data indicate that the membrane localizations of different P ...[more]