Ontology highlight
ABSTRACT:
SUBMITTER: Lord M
PROVIDER: S-EPMC2172548 | biostudies-literature | 2004 Oct
REPOSITORIES: biostudies-literature
Lord Matthew M Pollard Thomas D TD
The Journal of cell biology 20041001 2
We purified native Myo2p/Cdc4p/Rlc1p (Myo2), the myosin-II motor required for cytokinesis by Schizosaccharomyces pombe. The Myo2p heavy chain associates with two light chains, Cdc4p and Rlc1p. Although crude Myo2 supported gliding motility of actin filaments in vitro, purified Myo2 lacked this activity in spite of retaining full Ca-ATPase activity and partial actin-activated Mg-ATPase activity. Unc45-/Cro1p-/She4p-related (UCS) protein Rng3p restored the full motility and actin-activated Mg-ATPa ...[more]