Ontology highlight
ABSTRACT:
SUBMITTER: Salmon WC
PROVIDER: S-EPMC2173033 | biostudies-literature | 2002 Jul
REPOSITORIES: biostudies-literature
Salmon Wendy C WC Adams Michael C MC Waterman-Storer Clare M CM
The Journal of cell biology 20020708 1
Interactions between microtubules (MTs) and filamentous actin (f-actin) are involved in directed cell locomotion, but are poorly understood. To test the hypothesis that MTs and f-actin associate with one another and affect each other's organization and dynamics, we performed time-lapse dual-wavelength spinning-disk confocal fluorescent speckle microscopy (FSM) of MTs and f-actin in migrating newt lung epithelial cells. F-actin exhibited four zones of dynamic behavior: rapid retrograde flow in th ...[more]