Ontology highlight
ABSTRACT:
SUBMITTER: De Bari C
PROVIDER: S-EPMC2173757 | biostudies-literature | 2003 Mar
REPOSITORIES: biostudies-literature
De Bari Cosimo C Dell'Accio Francesco F Vandenabeele Frank F Vermeesch Joris R JR Raymackers Jean-Marc JM Luyten Frank P FP
The Journal of cell biology 20030310 6
We have demonstrated previously that adult human synovial membrane-derived mesenchymal stem cells (hSM-MSCs) have myogenic potential in vitro (De Bari, C., F. Dell'Accio, P. Tylzanowski, and F.P. Luyten. 2001. Arthritis Rheum. 44:1928-1942). In the present study, we have characterized their myogenic differentiation in a nude mouse model of skeletal muscle regeneration and provide proof of principle of their potential use for muscle repair in the mdx mouse model of Duchenne muscular dystrophy. Wh ...[more]