Human saliva proteome and transcriptome.
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ABSTRACT:
SUBMITTER: Hu S
PROVIDER: S-EPMC2175525 | biostudies-literature | 2006 Dec
REPOSITORIES: biostudies-literature
Publications
Human saliva proteome and transcriptome.
Hu S S Li Y Y Wang J J Xie Y Y Tjon K K Wolinsky L L Loo R R O RR Loo J A JA Wong D T DT
Journal of dental research 20061201 12
This paper tests the hypothesis that salivary proteins and their counterpart mRNAs co-exist in human whole saliva. Global profiling of human saliva proteomes and transcriptomes by mass spectrometry (MS) and expression microarray technologies, respectively, revealed many similarities between saliva proteins and mRNAs. Of the function-known proteins identified in saliva, from 61 to 70% were also found present as mRNA transcripts. For genes not detected at both protein and mRNA levels, we made furt ...[more]
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