Ontology highlight
ABSTRACT:
SUBMITTER: Shen Z
PROVIDER: S-EPMC21908 | biostudies-literature | 1999 May
REPOSITORIES: biostudies-literature
Shen Z Z Dimopoulos G G Kafatos F C FC Jacobs-Lorena M M
Proceedings of the National Academy of Sciences of the United States of America 19990501 10
An invertebrate intestinal mucin gene, AgMuc1, was isolated from the malaria vector mosquito Anopheles gambiae. The predicted 122-residue protein consists of a central core of seven repeating TTTTVAP motifs flanked by hydrophobic N- and C-terminal domains. This structure is similar to that of mucins that coat the protozoan parasite Trypanosoma cruzi. Northern blot analysis indicated that the gene is expressed exclusively in the midgut of adult mosquitoes. A length polymorphism and in situ hybrid ...[more]