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ABSTRACT:
SUBMITTER: Wittung-Stafshede P
PROVIDER: S-EPMC21958 | biostudies-literature | 1999 Jun
REPOSITORIES: biostudies-literature
Wittung-Stafshede P P Lee J C JC Winkler J R JR Gray H B HB
Proceedings of the National Academy of Sciences of the United States of America 19990601 12
Ferrocytochrome b562 [Fe(II)cyt b562] folding can be triggered by photoinduced electron transfer to unfolded Fe(III)cyt b562 in 2-3 M guanidine hydrochloride solutions. The folding rates increase with decreasing guanidine hydrochloride; the extrapolated time constant for this folding process in the absence of denaturant (5 micros) is near the predicted value for intrachain diffusion. The relatively smooth energy landscape indicated for Fe(II)cyt b562 folding accords with the helical, highly symm ...[more]