Ontology highlight
ABSTRACT:
SUBMITTER: Adams DJ
PROVIDER: S-EPMC2196870 | biostudies-literature | 2001 Jul
REPOSITORIES: biostudies-literature
Adams D J DJ van der Weyden L L Mayeda A A Stamm S S Morris B J BJ Rasko J E JE
The Journal of cell biology 20010701 1
The formation of the active spliceosome, its recruitment to active areas of transcription, and its role in pre-mRNA splicing depends on the association of a number of multifunctional serine/arginine-rich (SR) proteins. ZNF265 is an arginine/serine-rich (RS) domain containing zinc finger protein with conserved pre-mRNA splicing protein motifs. Here we show that ZNF265 immunoprecipitates from splicing extracts in association with mRNA, and that it is able to alter splicing patterns of Tra2-beta1 t ...[more]