Ontology highlight
ABSTRACT:
SUBMITTER: Stogios PJ
PROVIDER: S-EPMC2203294 | biostudies-literature | 2007 Feb
REPOSITORIES: biostudies-literature
Stogios Peter J PJ Chen Lu L Privé Gilbert G GG
Protein science : a publication of the Protein Society 20061222 2
BTB-zinc finger (BTB-ZF) proteins are transcription regulators with roles in development, differentiation, and oncogenesis. In these proteins, the BTB domain (also known as the POZ domain) is a protein-protein interaction motif that contains a dimerization interface, a possible oligomerization surface, and surfaces for interactions with other factors, including nuclear co-repressors and histone deacetylases. The BTB-ZF protein LRF (also known as ZBTB7, FBI-1, OCZF, and Pokemon) is a master regul ...[more]